What is Wu Ling Shen (Xylaria nigripes)
Wu Ling Shen, a folklore name for Xylaria nigripes, is a high value medicinal fungus has been used to regulating wake and sleep in traditional Chinese medicine since many years ago. Wu Ling Shen mainly spread in south-west China in Sichuan and Guizhou provinces. In modern researches, scientists show that Xylaria nigripes have a tranquilizing effect on the central nervous system, it could modulate some physiological functions such as anti-oxidative damage, anti-inflammatory activity and protecting carbon tetrachloride-induced liver injury in mice . And Xylaria nigripes is also used to relieving depression and treating trauma. Also scientists has identified some chemical constituents of Wu Ling Sheng, and these constituents include 5-hydroxy-7-methoxy-2-methyl-4-chromanone, 5, 7-dihydroxy-2-methyl-4-chromanone, 5-hydroxyl-2-methyl-4-chromanone, 1-(2, 6-dihydroxyphenyl)-3-hydroxybutanone, 5alpha, 8alpha-epidioxyergosta-6, 22-dien-3beta-ol, (22E,24R)-ergost-7, 22-dien-3beta, 5alpha, 6alpha-triol, euphorbol, beta-sitosterol and 2-(4-hydroxyphenyl) –ethanol.
Wu Ling Shen (Xylaria nigripes) Mushroom Powder Benefits
Although modren researches on the health benefits of taking Wu Ling Shen Powder are limited, some studies suggest that Wu Ling Shen may offer certain health benefits. Here’s a look at several key study findings:
Benefits for Neurogenic Systems
Xylaria Nigripes exerts effective protection against spatial memory impairment induced by rapid eye movement sleep deprivation in rats; Xylaria Nigripes is a potential effective drug to treat spatial memory impairment. Its act mechanism could be elevating phosphorylation of CREB in hippocampus. Also previous study have shown XN have good efficacies in treatment of insomnia.
Some researchers conclude that Xylaria Nigripes extract powder possesses a strong anti-inflammatory activity and its mechanism of action could be mediated by inhibiting iNOS and COX-2 expression via the NF-κB signaling pathway, and these activities could be contributed by the β-glucan content. And their results showed that treatment of macrophages with 5-30 μg/ml of Xylaria Nigripes water extract or Xylaria Nigripes ethanol extract plus 1 μg/ml lipopolysaccharide exhibited no cytotoxic effect on cell viability.
Recent studies have shown that Xylaria nigripes extract has strong anti-oxidant properties. In their studies, Xylaria nigripes extract could help to sweep away DPPH free-radical in human body. Also they believe the anti-oxidant properties of Xylaria nigripes extract is more potent than Trolox and vitamin C.
Wu Ling Shen (Xylaria nigripes) Mushroom Powder Side Effects
There is not enough reliable information to know if Wu Ling Shen Mycelium powder are safe for use as medicines. But there is not enough known about the use of Wu Ling Shen Mycelium powder during pregnancy and breast-feeding.
How to Take Wu Ling Shen (Xylaria nigripes) Mushroom Powder
The appropriate dose of Wu Ling Shen Mycelium powder on several factors such as the user’s age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for mangosteen. Below is the recommended dosage by the author: Taking 3-10g as daily dosage.
Where to buy high quality Wu Ling Shen (Xylaria nigripes) Mushroom Powder
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